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Inhibition of Interleukin 1β (IL-1β) Expression by Anthrax Lethal Toxin (LeTx) Is Reversed by Histone Deacetylase 8 (HDAC8) Inhibition in Murine Macrophages

Many pathogenic microbes often release toxins that subvert the host's immune responses to render the environment suitable for their survival and proliferation. LeTx is one of the toxins causing immune paralysis by cleaving and inactivating the mitogen-activated protein kinase (MAPK) kinases (ME...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Ha, Soon-Duck, Reid, Chantelle, Meshkibaf, Shahab, Kim, Sung Ouk
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861443/
https://ncbi.nlm.nih.gov/pubmed/26912657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695809
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