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HDAC8 Prevents Anthrax Lethal Toxin-induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells

Anthrax lethal toxin (LeTx) is a cytotoxic virulence factor that causes cell cycle arrest and cell death in various cell types. However, susceptibility to the cytotoxic effects varies depending on cell types. In proliferating monocytes, LeTx has only transient cytotoxic effects due to activation of...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Toxins (Basel)
Asıl Yazarlar: Ha, Soon-Duck, Cho, Woohyun, Kim, Sung Ouk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450710/
https://ncbi.nlm.nih.gov/pubmed/28509866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9050162
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