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HDAC8 Prevents Anthrax Lethal Toxin-induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells

Anthrax lethal toxin (LeTx) is a cytotoxic virulence factor that causes cell cycle arrest and cell death in various cell types. However, susceptibility to the cytotoxic effects varies depending on cell types. In proliferating monocytes, LeTx has only transient cytotoxic effects due to activation of...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Ha, Soon-Duck, Cho, Woohyun, Kim, Sung Ouk
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450710/
https://ncbi.nlm.nih.gov/pubmed/28509866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9050162
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