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HDAC8-mediated epigenetic reprogramming plays a key role in resistance to anthrax lethal toxin-induced pyroptosis in macrophages()
Macrophages pre-exposed to a sub-lethal dose of anthrax lethal toxin (LeTx) are refractory to subsequent high cytolytic doses of LeTx, termed toxin-induced resistance (TIR). A small population of TIR cells (2–4%) retains TIR characteristics for up to 5 to 6 weeks. Through studying these long-term TI...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108443/ https://ncbi.nlm.nih.gov/pubmed/24973453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400420 |
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