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A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices

Lysine acetylations are post-translational modifications of cellular proteins, that are crucial in the regulation of many cellular processes. Lysine acetylations on histone proteins are part of the epigenetic code regulating gene transcription and are installed by histone acetyltransferases. Observa...

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Detalhes bibliográficos
Publicado no:Pulm Pharmacol Ther
Main Authors: van den Bosch, Thea, Leus, Niek G. J., Wapenaar, Hannah, Boichenko, Alexander, Hermans, Jos, Bischoff, Rainer, Haisma, Hidde J., Dekker, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447808/
https://ncbi.nlm.nih.gov/pubmed/28323055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pupt.2017.03.006
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