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A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices

Lysine acetylations are post-translational modifications of cellular proteins, that are crucial in the regulation of many cellular processes. Lysine acetylations on histone proteins are part of the epigenetic code regulating gene transcription and are installed by histone acetyltransferases. Observa...

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Bibliografische gegevens
Gepubliceerd in:Pulm Pharmacol Ther
Hoofdauteurs: van den Bosch, Thea, Leus, Niek G. J., Wapenaar, Hannah, Boichenko, Alexander, Hermans, Jos, Bischoff, Rainer, Haisma, Hidde J., Dekker, Frank J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447808/
https://ncbi.nlm.nih.gov/pubmed/28323055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pupt.2017.03.006
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