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Tumor cell-intrinsic CD274/PD-L1: A novel metabolic balancing act with clinical potential
Tumor expression of the immune co-signaling molecule CD274/PD-L1 was originally described as impeding antitumor immunity by direct engagement of its receptor, PDCD1/PD-1, on antitumor T cells. Melanoma-intrinsic PDCD1 was recently shown to promote tumor growth and MTOR signals in cooperation with tu...
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5446070/ https://ncbi.nlm.nih.gov/pubmed/28368722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1280223 |
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