Tumor cell-intrinsic CD274/PD-L1: A novel metabolic balancing act with clinical potential

Tumor expression of the immune co-signaling molecule CD274/PD-L1 was originally described as impeding antitumor immunity by direct engagement of its receptor, PDCD1/PD-1, on antitumor T cells. Melanoma-intrinsic PDCD1 was recently shown to promote tumor growth and MTOR signals in cooperation with tu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Autophagy
Hlavní autoři: Clark, Curtis A., Gupta, Harshita B., Curiel, Tyler J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Autophagic Punctum
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446070/
https://ncbi.nlm.nih.gov/pubmed/28368722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1280223
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky