PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3

Glioblastoma (GBM) is the most lethal type of human brain cancer, where deletions and mutations in the tumour suppressor gene PTEN (phosphatase and tensin homolog) are frequent events and are associated with therapeutic resistance. Herein, we report a novel chromatin-associated function of PTEN in c...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Benitez, Jorge A., Ma, Jianhui, D’Antonio, Matteo, Boyer, Antonia, Camargo, Maria Fernanda, Zanca, Ciro, Kelly, Stephen, Khodadadi-Jamayran, Alireza, Jameson, Nathan M., Andersen, Michael, Miletic, Hrvoje, Saberi, Shahram, Frazer, Kelly A., Cavenee, Webster K., Furnari, Frank B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437297/
https://ncbi.nlm.nih.gov/pubmed/28497778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15223
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