PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3

Glioblastoma (GBM) is the most lethal type of human brain cancer, where deletions and mutations in the tumour suppressor gene PTEN (phosphatase and tensin homolog) are frequent events and are associated with therapeutic resistance. Herein, we report a novel chromatin-associated function of PTEN in c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Benitez, Jorge A., Ma, Jianhui, D’Antonio, Matteo, Boyer, Antonia, Camargo, Maria Fernanda, Zanca, Ciro, Kelly, Stephen, Khodadadi-Jamayran, Alireza, Jameson, Nathan M., Andersen, Michael, Miletic, Hrvoje, Saberi, Shahram, Frazer, Kelly A., Cavenee, Webster K., Furnari, Frank B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437297/
https://ncbi.nlm.nih.gov/pubmed/28497778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15223
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados