Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

The T-cell protein tyrosine phosphatase (TCPTP) pathway consists of signaling events mediated by TCPTP. Mutations and genetic variants of some genes in the TCPTP pathway are associated with lung cancer risk and survival. In the present study, we first investigated associations of 5,162 single nucleo...

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Udgivet i:Sci Rep
Main Authors: Feng, Yun, Wang, Yanru, Liu, Hongliang, Liu, Zhensheng, Mills, Coleman, Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeboeller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil E., Teresa Landi, Maria, Brueske, Irene, Risch, Angela, Ye, Yuanqing, Wu, Xifeng, Christiani, David C., Amos, Christopher I., Wei, Qingyi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429754/
https://ncbi.nlm.nih.gov/pubmed/28400551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00850-0
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