Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs

mRNA splicing is an important mechanism to regulate mRNA expression. Abnormal regulation of this process may lead to lung cancer. Here, we investigated the associations of 11,966 single-nucleotide polymorphisms (SNPs) in 206 mRNA splicing-related genes with lung cancer risk by using the summary data...

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書誌詳細
出版年:Sci Rep
主要な著者: Pan, Yongchu, Liu, Hongliang, Wang, Yanru, Kang, Xiaozheng, Liu, Zhensheng, Owzar, Kouros, Han, Younghun, Su, Li, Wei, Yongyue, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeböller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil, Teresa Landi, Maria, Heinrich, Joachim, Risch, Angela, Wu, Xifeng, Ye, Yuanqing, Christiani, David C., Amos, Christopher I., Wei, Qingyi
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356340/
https://ncbi.nlm.nih.gov/pubmed/28304396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44634
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