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Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

The T-cell protein tyrosine phosphatase (TCPTP) pathway consists of signaling events mediated by TCPTP. Mutations and genetic variants of some genes in the TCPTP pathway are associated with lung cancer risk and survival. In the present study, we first investigated associations of 5,162 single nucleo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Feng, Yun, Wang, Yanru, Liu, Hongliang, Liu, Zhensheng, Mills, Coleman, Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeboeller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil E., Teresa Landi, Maria, Brueske, Irene, Risch, Angela, Ye, Yuanqing, Wu, Xifeng, Christiani, David C., Amos, Christopher I., Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429754/
https://ncbi.nlm.nih.gov/pubmed/28400551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00850-0
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