Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

The T-cell protein tyrosine phosphatase (TCPTP) pathway consists of signaling events mediated by TCPTP. Mutations and genetic variants of some genes in the TCPTP pathway are associated with lung cancer risk and survival. In the present study, we first investigated associations of 5,162 single nucleo...

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Pubblicato in:Sci Rep
Autori principali: Feng, Yun, Wang, Yanru, Liu, Hongliang, Liu, Zhensheng, Mills, Coleman, Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeboeller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil E., Teresa Landi, Maria, Brueske, Irene, Risch, Angela, Ye, Yuanqing, Wu, Xifeng, Christiani, David C., Amos, Christopher I., Wei, Qingyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429754/
https://ncbi.nlm.nih.gov/pubmed/28400551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00850-0
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