Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

Large-scale genome-wide association studies (GWAS) have likely uncovered all common variants at the GWAS significance level. Additional variants within the suggestive range (0.0001> P > 5×10(−8)) are, however, still of interest for identifying causal associations. This analysis aimed to apply...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Brenner, Darren R., Amos, Christopher I., Brhane, Yonathan, Timofeeva, Maria N., Caporaso, Neil, Wang, Yufei, Christiani, David C., Bickeböller, Heike, Yang, Ping, Albanes, Demetrius, Stevens, Victoria L., Gapstur, Susan, McKay, James, Boffetta, Paolo, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Krokan, Hans E., Skorpen, Frank, Gabrielsen, Maiken E., Vatten, Lars, Njølstad, Inger, Chen, Chu, Goodman, Gary, Lathrop, Mark, Vooder, Tõnu, Välk, Kristjan, Nelis, Mari, Metspalu, Andres, Broderick, Peter, Eisen, Timothy, Wu, Xifeng, Zhang, Di, Chen, Wei, Spitz, Margaret R., Wei, Yongyue, Su, Li, Xie, Dong, She, Jun, Matsuo, Keitaro, Matsuda, Fumihiko, Ito, Hidemi, Risch, Angela, Heinrich, Joachim, Rosenberger, Albert, Muley, Thomas, Dienemann, Hendrik, Field, John K., Raji, Olaide, Chen, Ying, Gosney, John, Liloglou, Triantafillos, Davies, Michael P.A., Marcus, Michael, McLaughlin, John, Orlow, Irene, Han, Younghun, Li, Yafang, Zong, Xuchen, Johansson, Mattias, Liu, Geoffrey, Tworoger, Shelley S., Le Marchand, Loic, Henderson, Brian E., Wilkens, Lynne R., Dai, Juncheng, Shen, Hongbing, Houlston, Richard S., Landi, Maria T., Brennan, Paul, Hung, Rayjean J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635669/
https://ncbi.nlm.nih.gov/pubmed/26363033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv128
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