Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

Large-scale genome-wide association studies (GWAS) have likely uncovered all common variants at the GWAS significance level. Additional variants within the suggestive range (0.0001> P > 5×10(−8)) are, however, still of interest for identifying causal associations. This analysis aimed to apply...

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Published in:Carcinogenesis
Main Authors: Brenner, Darren R., Amos, Christopher I., Brhane, Yonathan, Timofeeva, Maria N., Caporaso, Neil, Wang, Yufei, Christiani, David C., Bickeböller, Heike, Yang, Ping, Albanes, Demetrius, Stevens, Victoria L., Gapstur, Susan, McKay, James, Boffetta, Paolo, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Krokan, Hans E., Skorpen, Frank, Gabrielsen, Maiken E., Vatten, Lars, Njølstad, Inger, Chen, Chu, Goodman, Gary, Lathrop, Mark, Vooder, Tõnu, Välk, Kristjan, Nelis, Mari, Metspalu, Andres, Broderick, Peter, Eisen, Timothy, Wu, Xifeng, Zhang, Di, Chen, Wei, Spitz, Margaret R., Wei, Yongyue, Su, Li, Xie, Dong, She, Jun, Matsuo, Keitaro, Matsuda, Fumihiko, Ito, Hidemi, Risch, Angela, Heinrich, Joachim, Rosenberger, Albert, Muley, Thomas, Dienemann, Hendrik, Field, John K., Raji, Olaide, Chen, Ying, Gosney, John, Liloglou, Triantafillos, Davies, Michael P.A., Marcus, Michael, McLaughlin, John, Orlow, Irene, Han, Younghun, Li, Yafang, Zong, Xuchen, Johansson, Mattias, Liu, Geoffrey, Tworoger, Shelley S., Le Marchand, Loic, Henderson, Brian E., Wilkens, Lynne R., Dai, Juncheng, Shen, Hongbing, Houlston, Richard S., Landi, Maria T., Brennan, Paul, Hung, Rayjean J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635669/
https://ncbi.nlm.nih.gov/pubmed/26363033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv128
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