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Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

Large-scale genome-wide association studies (GWAS) have likely uncovered all common variants at the GWAS significance level. Additional variants within the suggestive range (0.0001> P > 5×10(−8)) are, however, still of interest for identifying causal associations. This analysis aimed to apply...

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Publicat a:Carcinogenesis
Autors principals: Brenner, Darren R., Amos, Christopher I., Brhane, Yonathan, Timofeeva, Maria N., Caporaso, Neil, Wang, Yufei, Christiani, David C., Bickeböller, Heike, Yang, Ping, Albanes, Demetrius, Stevens, Victoria L., Gapstur, Susan, McKay, James, Boffetta, Paolo, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Krokan, Hans E., Skorpen, Frank, Gabrielsen, Maiken E., Vatten, Lars, Njølstad, Inger, Chen, Chu, Goodman, Gary, Lathrop, Mark, Vooder, Tõnu, Välk, Kristjan, Nelis, Mari, Metspalu, Andres, Broderick, Peter, Eisen, Timothy, Wu, Xifeng, Zhang, Di, Chen, Wei, Spitz, Margaret R., Wei, Yongyue, Su, Li, Xie, Dong, She, Jun, Matsuo, Keitaro, Matsuda, Fumihiko, Ito, Hidemi, Risch, Angela, Heinrich, Joachim, Rosenberger, Albert, Muley, Thomas, Dienemann, Hendrik, Field, John K., Raji, Olaide, Chen, Ying, Gosney, John, Liloglou, Triantafillos, Davies, Michael P.A., Marcus, Michael, McLaughlin, John, Orlow, Irene, Han, Younghun, Li, Yafang, Zong, Xuchen, Johansson, Mattias, Liu, Geoffrey, Tworoger, Shelley S., Le Marchand, Loic, Henderson, Brian E., Wilkens, Lynne R., Dai, Juncheng, Shen, Hongbing, Houlston, Richard S., Landi, Maria T., Brennan, Paul, Hung, Rayjean J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635669/
https://ncbi.nlm.nih.gov/pubmed/26363033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgv128
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