Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk - a re-analysis of eight GWASs

PURPOSE: mRNA degradation is an important regulatory step for controlling gene expression and cell functions. Genetic abnormalities of the genes involved in mRNA degradation were found to be associated with cancer risks. Therefore, we systematically investigated the roles of genetic variants of gene...

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Pubblicato in:Mol Carcinog
Autori principali: Zhou, Fei, Wang, Yanru, Liu, Hongliang, Ready, Neal, Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeböller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil, Landi, Maria Teresa, Brüske, Irene, Risch, Angela, Ye, Yuanqing, Wu, Xifeng, Christiani, David C., Goodman, Gary, Chen, Chu, Amos, Christopher I., Qingyi, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354966/
https://ncbi.nlm.nih.gov/pubmed/27805284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22585
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