Functional variants in DCAF4 associated with lung cancer risk in European populations

Cullin-RING ubiquitin ligases (CRLs) responsible for substrate specificity of ubiquitination play a key role in cell-cycle control and DNA damage response. In this study, we assessed associations between 16 599 SNPs in 115 CRL genes and lung cancer risk by using summary data of six published genome-...

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Vydáno v:Carcinogenesis
Hlavní autoři: Liu, Hongliang, Liu, Zhensheng, Wang, Yanru, Stinchcombe, Thomas E., Owzar, Kouros, Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeböller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil, Landi, Maria T., Brüske, Irene, Risch, Angela, Wu, Xifeng, Ye, Yuanqing, Christiani, David C., Amos, Christopher I., Wei, Qingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074950/
https://ncbi.nlm.nih.gov/pubmed/28383684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx033
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