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Structural Insights into Aldosterone Synthase Substrate Specificity and Targeted Inhibition
Aldosterone is a major mineralocorticoid hormone that plays a key role in the regulation of electrolyte balance and blood pressure. Excess aldosterone levels can arise from dysregulation of the renin-angiotensin-aldosterone system and are implicated in the pathogenesis of hypertension and heart fail...
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| 出版年: | Mol Endocrinol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Endocrine Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417327/ https://ncbi.nlm.nih.gov/pubmed/23322723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1287 |
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