Ataxin-3 promotes genome integrity by stabilizing Chk1

The Chk1 protein is essential for genome integrity maintenance and cell survival in eukaryotic cells. After prolonged replication stress, Chk1 can be targeted for proteasomal degradation to terminate checkpoint signaling after DNA repair finishes. To ensure proper activation of DNA damage checkpoint...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tu, Yingfeng, Liu, Hongmei, Zhu, Xuefei, Shen, Hongyan, Ma, Xiaolu, Wang, Fengli, Huang, Min, Gong, Juanjuan, Li, Xiaoling, Wang, Yun, Guo, Caixia, Tang, Tie-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416811/
https://ncbi.nlm.nih.gov/pubmed/28180282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx095
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados