Parkin regulates translesion DNA synthesis in response to UV radiation

Deficiency of Parkin is a major cause of early-onset Parkinson's disease (PD). Notably, PD patients also exhibit a significantly higher risk in melanoma and other skin tumors, while the mechanism remains largely unknown. In this study, we show that depletion of Parkin causes compromised cell vi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Zhu, Xuefei, Ma, Xiaolu, Tu, Yingfeng, Huang, Min, Liu, Hongmei, Wang, Fengli, Gong, Juanjuan, Wang, Jiuqiang, Li, Xiaoling, Chen, Qian, Shen, Hongyan, Zhu, Shu, Wang, Yun, Liu, Yang, Guo, Caixia, Tang, Tie-Shan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482665/
https://ncbi.nlm.nih.gov/pubmed/28430587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16855
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