Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation

Translesion DNA synthesis (TLS) can use specialized DNA polymerases to insert and/or extend nucleotides across lesions, thereby limiting stalled replication fork collapse and the potential for cell death. Recent studies have shown that monoubiquitinated proliferating cell nuclear antigen (PCNA) play...

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Hlavní autoři: Lv, Lingna, Wang, Fengli, Ma, Xiaolu, Yang, Yeran, Wang, Zhifeng, Liu, Hongmei, Li, Xiaoling, Liu, Zhenbo, Zhang, Ting, Huang, Min, Friedberg, Errol C., Tang, Tie-Shan, Guo, Caixia
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905884/
https://ncbi.nlm.nih.gov/pubmed/24038355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt793
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