RNA-splicing factor SART3 regulates translesion DNA synthesis

Translesion DNA synthesis (TLS) is one mode of DNA damage tolerance that uses specialized DNA polymerases to replicate damaged DNA. DNA polymerase η (Polη) is well known to facilitate TLS across ultraviolet (UV) irradiation and mutations in POLH are implicated in skin carcinogenesis. However, the ba...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Huang, Min, Zhou, Bo, Gong, Juanjuan, Xing, Lingyu, Ma, Xiaolu, Wang, Fengli, Wu, Wei, Shen, Hongyan, Sun, Chenyi, Zhu, Xuefei, Yang, Yeran, Sun, Yazhou, Liu, Yang, Tang, Tie-Shan, Guo, Caixia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961147/
https://ncbi.nlm.nih.gov/pubmed/29590477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky220
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