Parkin regulates translesion DNA synthesis in response to UV radiation

Deficiency of Parkin is a major cause of early-onset Parkinson's disease (PD). Notably, PD patients also exhibit a significantly higher risk in melanoma and other skin tumors, while the mechanism remains largely unknown. In this study, we show that depletion of Parkin causes compromised cell vi...

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Vydáno v:Oncotarget
Hlavní autoři: Zhu, Xuefei, Ma, Xiaolu, Tu, Yingfeng, Huang, Min, Liu, Hongmei, Wang, Fengli, Gong, Juanjuan, Wang, Jiuqiang, Li, Xiaoling, Chen, Qian, Shen, Hongyan, Zhu, Shu, Wang, Yun, Liu, Yang, Guo, Caixia, Tang, Tie-Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482665/
https://ncbi.nlm.nih.gov/pubmed/28430587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16855
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