MEPE/OF45 protects cells from DNA damage induced killing via stabilizing CHK1

Matrix extracellular phosphoglycoprotein/osteoblast factor 45 (MEPE/OF45) was cloned in 2000 with functions related to bone metabolism. We identified MEPE/OF45 for the first time as a new co-factor of CHK1 in mammalian cells to protect cells from DNA damage induced killing. We demonstrate here that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Shuang, Wang, Hongyan, Wang, Xiang, Lu, Lin, Gao, Ning, Rowe, Peter S. N., Hu, Baocheng, Wang, Ya
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794162/
https://ncbi.nlm.nih.gov/pubmed/19808933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp768
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