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Structural insight to mutation effects uncover a common allosteric site in class C GPCRs
MOTIVATION: Class C G protein-coupled receptors (GPCRs) regulate important physiological functions and allosteric modulators binding to the transmembrane domain constitute an attractive and, due to a lack of structural insight, a virtually unexplored potential for therapeutics and the food industry....
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5408886/ https://ncbi.nlm.nih.gov/pubmed/28011766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw784 |
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