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Allosteric Modulation of GPCRs of Class A by Cholesterol

G-protein coupled receptors (GPCRs) are membrane proteins that convey extracellular signals to the cellular milieu. They represent a target for more than 30% of currently marketed drugs. Here we review the effects of membrane cholesterol on the function of GPCRs of Class A. We review both the specif...

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Pubblicato in:Int J Mol Sci
Autori principali: Jakubík, Jan, El-Fakahany, Esam E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920425/
https://ncbi.nlm.nih.gov/pubmed/33669406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041953
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