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Current Advances in Allosteric Modulation of Muscarinic Receptors

Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter. Allosteric modulators modulate the binding affinity, potency, and efficacy of orthosteric ligands. Muscarinic acetylcholine recepto...

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Détails bibliographiques
Publié dans:Biomolecules
Auteurs principaux: Jakubik, Jan, El-Fakahany, Esam E.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072599/
https://ncbi.nlm.nih.gov/pubmed/32085536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020325
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