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Current Advances in Allosteric Modulation of Muscarinic Receptors

Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter. Allosteric modulators modulate the binding affinity, potency, and efficacy of orthosteric ligands. Muscarinic acetylcholine recepto...

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Detalles Bibliográficos
Publicado en:Biomolecules
Main Authors: Jakubik, Jan, El-Fakahany, Esam E.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072599/
https://ncbi.nlm.nih.gov/pubmed/32085536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020325
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