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Current Advances in Allosteric Modulation of Muscarinic Receptors

Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter. Allosteric modulators modulate the binding affinity, potency, and efficacy of orthosteric ligands. Muscarinic acetylcholine recepto...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Jakubik, Jan, El-Fakahany, Esam E.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072599/
https://ncbi.nlm.nih.gov/pubmed/32085536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020325
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