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Current Advances in Allosteric Modulation of Muscarinic Receptors

Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter. Allosteric modulators modulate the binding affinity, potency, and efficacy of orthosteric ligands. Muscarinic acetylcholine recepto...

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Bibliografische gegevens
Gepubliceerd in:Biomolecules
Hoofdauteurs: Jakubik, Jan, El-Fakahany, Esam E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072599/
https://ncbi.nlm.nih.gov/pubmed/32085536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020325
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