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Current Advances in Allosteric Modulation of Muscarinic Receptors

Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter. Allosteric modulators modulate the binding affinity, potency, and efficacy of orthosteric ligands. Muscarinic acetylcholine recepto...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Jakubik, Jan, El-Fakahany, Esam E.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072599/
https://ncbi.nlm.nih.gov/pubmed/32085536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020325
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