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Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors

BACKGROUND: Many neuromuscular blockers act as negative allosteric modulators of muscarinic acetylcholine receptors by decreasing affinity and potency of acetylcholine. The neuromuscular blocker rapacuronium has been shown to have facilitatory effects at muscarinic receptors leading to bronchospasm....

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Detalhes bibliográficos
Main Authors: Jakubík, Jan, Randáková, Alena, El-Fakahany, Esam E, Doležal, Vladimír
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806265/
https://ncbi.nlm.nih.gov/pubmed/20038295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-15
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