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Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors

BACKGROUND: Many neuromuscular blockers act as negative allosteric modulators of muscarinic acetylcholine receptors by decreasing affinity and potency of acetylcholine. The neuromuscular blocker rapacuronium has been shown to have facilitatory effects at muscarinic receptors leading to bronchospasm....

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Hlavní autoři: Jakubík, Jan, Randáková, Alena, El-Fakahany, Esam E, Doležal, Vladimír
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806265/
https://ncbi.nlm.nih.gov/pubmed/20038295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-9-15
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