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Positive allosteric modulators to peptide GPCRs: a promising class of drugs

The task of finding selective and stable peptide receptor agonists with low molecular weight, desirable pharmacokinetic properties and penetrable to the blood-brain barrier has proven too difficult for many highly coveted drug targets, including receptors for endothelin, vasoactive intestinal peptid...

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Bibliografiske detaljer
Main Authors: Bartfai, Tamas, Wang, Ming-wei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002610/
https://ncbi.nlm.nih.gov/pubmed/23624758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.20
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