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Positive allosteric modulators to peptide GPCRs: a promising class of drugs
The task of finding selective and stable peptide receptor agonists with low molecular weight, desirable pharmacokinetic properties and penetrable to the blood-brain barrier has proven too difficult for many highly coveted drug targets, including receptors for endothelin, vasoactive intestinal peptid...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002610/ https://ncbi.nlm.nih.gov/pubmed/23624758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.20 |
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