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Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts

G-protein-coupled receptors (GPCRs) have been tractable drug targets for decades with over one-third of currently marketed drugs targeting GPCRs. Of these, the class A GPCR superfamily is highly represented, and continued drug discovery for this family of receptors may provide novel therapeutics for...

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Bibliographische Detailangaben
Veröffentlicht in:J Med Chem
Hauptverfasser: Wold, Eric A., Chen, Jianping, Cunningham, Kathryn A., Zhou, Jia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556150/
https://ncbi.nlm.nih.gov/pubmed/30106578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b00875
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