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Curcumin Dictates Divergent Fates for the Central Salt Bridges in Amyloid-β(40) and Amyloid-β(42)
There are three specific regions in the Amyloid beta (Aβ) peptide sequence where variations cause enhanced toxicity in Alzheimer’s disease: the N-terminus, the central salt bridge, and the C-terminus. Here, we investigate if there is a close conformational connection between these three regions, whi...
Tallennettuna:
| Julkaisussa: | Biophys J |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Biophysical Society
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406280/ https://ncbi.nlm.nih.gov/pubmed/28445751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.043 |
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