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On the Stability of the Soluble Amyloid Aggregates

Many amyloid proteins form metastable soluble aggregates (or protofibrils, or protein nanoparticles, with characteristic sizes from ∼10 to a few hundred nm). These can coexist with protein monomers and amyloid precipitates. These soluble aggregates are key determinants of the toxicity of these prote...

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Detalhes bibliográficos
Main Authors: Sahoo, Bankanidhi, Nag, Suman, Sengupta, Parijat, Maiti, Sudipta
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749744/
https://ncbi.nlm.nih.gov/pubmed/19720034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.055
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