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Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest

During mitosis, cells must segregate the replicated copies of their genome to their daughter cells with extremely high fidelity. Segregation errors lead to an abnormal chromosome number (aneuploidy), which typically results in disease or cell death [1]. Chromosome segregation and anaphase onset are...

詳細記述

保存先:
書誌詳細
出版年:Curr Biol
主要な著者: May, Karen M., Paldi, Flora, Hardwick, Kevin G.
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405113/
https://ncbi.nlm.nih.gov/pubmed/28366744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.03.013
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