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Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism

BACKGROUND: Cells control progression through late mitosis by regulating Cdc20 and Cdh1, the two mitotic activators of the Anaphase Promoting Complex (APC). The control of Cdc20 protein levels during the cell cycle is not well understood. RESULTS: Here, we demonstrate that Cdc20 is degraded in buddi...

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Bibliographic Details
Main Authors: Foe, Ian T., Foster, Scott A., Cheung, Stephanie K., DeLuca, Steven Z., Morgan, David O., Toczyski, David P.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430386/
https://ncbi.nlm.nih.gov/pubmed/22079111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.09.051
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