A Cdc20-APC Ubiquitin Signaling Pathway Regulates Presynaptic Differentiation

Presynaptic axonal differentiation is essential for synapse formation and the establishment of neuronal circuits. However, the mechanisms that coordinate presynaptic development in the brain are largely unknown. Here, we found the major mitotic E3 ubiquitin ligase Cdc20-anaphase promoting complex (C...

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Main Authors: Yang, Yue, Kim, Albert, Yamada, Tomoko, Wu, Bei, Bilimoria, Parizad, Ikeuchi, Yoshiho, de la Iglesia, Núria, Shen, Jie, Bonni, Azad
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846784/
https://ncbi.nlm.nih.gov/pubmed/19900895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1177087
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