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A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons
The ubiquitin ligase anaphase-promoting complex (APC) recruits the coactivator Cdc20 to drive mitosis in cycling cells. However, the nonmitotic functions of Cdc20-APC have remained unexplored. We report that Cdc20-APC plays an essential role in dendrite morphogenesis in postmitotic neurons. Knockdow...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707082/ https://ncbi.nlm.nih.gov/pubmed/19167333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.11.050 |
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