Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus

While azole drugs targeting the biosynthesis of ergosterol are effective antifungal agents, their extensive use has led to the development of resistant organisms. Infections involving azole-resistant forms of the filamentous fungus Aspergillus fumigatus are often associated with genetic changes in t...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Paul, Sanjoy, Diekema, Daniel, Moye-Rowley, W. Scott
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404575/
https://ncbi.nlm.nih.gov/pubmed/28264842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02748-16
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