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A Novel Combination of CYP51A Mutations Confers Pan-Azole Resistance in Aspergillus fumigatus

The treatment of invasive and chronic aspergillosis involves triazole drugs. Its intensive use has resulted in the selection of resistant isolates, and at present, azole resistance in Aspergillus fumigatus is considered an emerging threat to public health worldwide. The aim of this work is to uncove...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Macedo, Daiana, Brito Devoto, Tomás, Pola, Santiago, Finquelievich, Jorge L., Cuestas, María L., Garcia-Effron, Guillermo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526825/
https://ncbi.nlm.nih.gov/pubmed/32423948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02501-19
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