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Uncovering New Mutations Conferring Azole Resistance in the Aspergillus fumigatus cyp51A Gene

The opportunistic pathogen Aspergillus fumigatus has developed worldwide resistance to azoles largely through mutations in cytochromeP450 enzyme Cyp51. In this study, we indicated that in vitro azole situation results in emergence of azole-resistant mutations. There are previously identified azole-r...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Chen, Peiying, Liu, Musang, Zeng, Qiuqiong, Zhang, Zheng, Liu, Weida, Sang, Hong, Lu, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986205/
https://ncbi.nlm.nih.gov/pubmed/32038564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03127
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