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Uncovering New Mutations Conferring Azole Resistance in the Aspergillus fumigatus cyp51A Gene

The opportunistic pathogen Aspergillus fumigatus has developed worldwide resistance to azoles largely through mutations in cytochromeP450 enzyme Cyp51. In this study, we indicated that in vitro azole situation results in emergence of azole-resistant mutations. There are previously identified azole-r...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Chen, Peiying, Liu, Musang, Zeng, Qiuqiong, Zhang, Zheng, Liu, Weida, Sang, Hong, Lu, Ling
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986205/
https://ncbi.nlm.nih.gov/pubmed/32038564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03127
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