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Uncovering New Mutations Conferring Azole Resistance in the Aspergillus fumigatus cyp51A Gene

The opportunistic pathogen Aspergillus fumigatus has developed worldwide resistance to azoles largely through mutations in cytochromeP450 enzyme Cyp51. In this study, we indicated that in vitro azole situation results in emergence of azole-resistant mutations. There are previously identified azole-r...

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Vydáno v:Front Microbiol
Hlavní autoři: Chen, Peiying, Liu, Musang, Zeng, Qiuqiong, Zhang, Zheng, Liu, Weida, Sang, Hong, Lu, Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986205/
https://ncbi.nlm.nih.gov/pubmed/32038564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03127
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