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In Vitro Biochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus
The incidence of triazole-resistant Aspergillus infections is increasing worldwide, often mediated through mutations in the CYP51A amino acid sequence. New classes of azole-based drugs are required to combat the increasing resistance to existing triazole therapeutics. In this study, a CYP51 reconsti...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Antimicrob Agents Chemother |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4649140/ https://ncbi.nlm.nih.gov/pubmed/26459890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01806-15 |
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