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A Novel Combination of CYP51A Mutations Confers Pan-Azole Resistance in Aspergillus fumigatus

The treatment of invasive and chronic aspergillosis involves triazole drugs. Its intensive use has resulted in the selection of resistant isolates, and at present, azole resistance in Aspergillus fumigatus is considered an emerging threat to public health worldwide. The aim of this work is to uncove...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Macedo, Daiana, Brito Devoto, Tomás, Pola, Santiago, Finquelievich, Jorge L., Cuestas, María L., Garcia-Effron, Guillermo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526825/
https://ncbi.nlm.nih.gov/pubmed/32423948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02501-19
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