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Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus

While azole drugs targeting the biosynthesis of ergosterol are effective antifungal agents, their extensive use has led to the development of resistant organisms. Infections involving azole-resistant forms of the filamentous fungus Aspergillus fumigatus are often associated with genetic changes in t...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Paul, Sanjoy, Diekema, Daniel, Moye-Rowley, W. Scott
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404575/
https://ncbi.nlm.nih.gov/pubmed/28264842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02748-16
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