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AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus
Aspergillosis associated with azole-resistant Aspergillus fumigatus has a mortality rate that can approach 90% in certain patient populations. The best-understood avenue for azole resistance involves changes in the cyp51A gene that encodes the target of azole drugs, lanosterol α-14 demethylase. The...
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| Publicado no: | mBio |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6414702/ https://ncbi.nlm.nih.gov/pubmed/30862750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02563-18 |
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