A Novel Zn(2)-Cys(6) Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for aspergillosis, have been widely disseminated across...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hagiwara, Daisuke, Miura, Daisuke, Shimizu, Kiminori, Paul, Sanjoy, Ohba, Ayumi, Gonoi, Tohru, Watanabe, Akira, Kamei, Katsuhiko, Shintani, Takahiro, Moye-Rowley, W. Scott, Kawamoto, Susumu, Gomi, Katsuya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215518/
https://ncbi.nlm.nih.gov/pubmed/28052140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006096
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