A Novel Zn(2)-Cys(6) Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for aspergillosis, have been widely disseminated across...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Hagiwara, Daisuke, Miura, Daisuke, Shimizu, Kiminori, Paul, Sanjoy, Ohba, Ayumi, Gonoi, Tohru, Watanabe, Akira, Kamei, Katsuhiko, Shintani, Takahiro, Moye-Rowley, W. Scott, Kawamoto, Susumu, Gomi, Katsuya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215518/
https://ncbi.nlm.nih.gov/pubmed/28052140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006096
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