A Novel Zn(2)-Cys(6) Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions

Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an increasing incidence of drug resistance. This situation is further complicated by the finding that strains resistant to azoles, the major antifungal drugs for aspergillosis, have been widely disseminated across...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Hagiwara, Daisuke, Miura, Daisuke, Shimizu, Kiminori, Paul, Sanjoy, Ohba, Ayumi, Gonoi, Tohru, Watanabe, Akira, Kamei, Katsuhiko, Shintani, Takahiro, Moye-Rowley, W. Scott, Kawamoto, Susumu, Gomi, Katsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215518/
https://ncbi.nlm.nih.gov/pubmed/28052140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006096
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge