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Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus

While azole drugs targeting the biosynthesis of ergosterol are effective antifungal agents, their extensive use has led to the development of resistant organisms. Infections involving azole-resistant forms of the filamentous fungus Aspergillus fumigatus are often associated with genetic changes in t...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Paul, Sanjoy, Diekema, Daniel, Moye-Rowley, W. Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404575/
https://ncbi.nlm.nih.gov/pubmed/28264842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02748-16
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