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Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus

While azole drugs targeting the biosynthesis of ergosterol are effective antifungal agents, their extensive use has led to the development of resistant organisms. Infections involving azole-resistant forms of the filamentous fungus Aspergillus fumigatus are often associated with genetic changes in t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Paul, Sanjoy, Diekema, Daniel, Moye-Rowley, W. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404575/
https://ncbi.nlm.nih.gov/pubmed/28264842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02748-16
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