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Curcumol allosterically modulates GABA(A) receptors in a manner distinct from benzodiazepines

Inhibitory A type γ-aminobutyric acid receptors (GABA(A)Rs) play a pivotal role in orchestrating various brain functions and represent an important molecular target in neurological and psychiatric diseases, necessitating the need for the discovery and development of novel modulators. Here, we show t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Liu, Yan-Mei, Fan, Hui-Ran, Ding, Jing, Huang, Chen, Deng, Shining, Zhu, Tailin, Xu, Tian-Le, Ge, Wei-Hong, Li, Wei-Guang, Li, Fei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402396/
https://ncbi.nlm.nih.gov/pubmed/28436443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46654
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