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Curcumol allosterically modulates GABA(A) receptors in a manner distinct from benzodiazepines

Inhibitory A type γ-aminobutyric acid receptors (GABA(A)Rs) play a pivotal role in orchestrating various brain functions and represent an important molecular target in neurological and psychiatric diseases, necessitating the need for the discovery and development of novel modulators. Here, we show t...

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書目詳細資料
發表在:Sci Rep
Main Authors: Liu, Yan-Mei, Fan, Hui-Ran, Ding, Jing, Huang, Chen, Deng, Shining, Zhu, Tailin, Xu, Tian-Le, Ge, Wei-Hong, Li, Wei-Guang, Li, Fei
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402396/
https://ncbi.nlm.nih.gov/pubmed/28436443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46654
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