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Structural Determinants of Benzodiazepine Allosteric Regulation of GABA(A) Receptor Currents
Benzodiazepine enhancement of GABA(A) receptor current requires a γ subunit, and replacement of the γ subunit by the δ subunit abolishes benzodiazepine enhancement. Although it has been demonstrated that benzodiazepines bind to GABA(A) receptors at the junction between α and γ subunits, the structur...
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| Publié dans: | J Neurosci |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725463/ https://ncbi.nlm.nih.gov/pubmed/16135763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0348-05.2005 |
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