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Structural Determinants of Benzodiazepine Allosteric Regulation of GABA(A) Receptor Currents

Benzodiazepine enhancement of GABA(A) receptor current requires a γ subunit, and replacement of the γ subunit by the δ subunit abolishes benzodiazepine enhancement. Although it has been demonstrated that benzodiazepines bind to GABA(A) receptors at the junction between α and γ subunits, the structur...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Jones-Davis, Dorothy M., Song, Luyan, Gallagher, Martin J., Macdonald, Robert L.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725463/
https://ncbi.nlm.nih.gov/pubmed/16135763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0348-05.2005
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